0001415889-21-004864 4 1 20211011 20211013 20211013 Bruck Claudine 0001733680 4 34 001-39202 211321277 4995 BRADENTON AVE, SUITE 240 DUBLIN OH 43017-3552 Annovis Bio, Inc. 0001477845 2834 262540421 DE 1231 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 610-727-3913 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 QR Pharma, Inc. 20091202 4 1 form4-10132021_011056.xml X0306 4 2021-10-11 0001477845 Annovis Bio, Inc. ANVS 0001733680 Bruck Claudine C/O ANNOVIS BIO, INC. 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 true false false false Common Stock 2021-10-11 4 P 0 181 27.66 A 6067 D /s/ Jeffrey McGroarty, Attorney-in-Fact for Claudine Bruck 2021-10-13