0001104659-20-010939 4 1 20200131 20200205 20200205 Maccecchini Maria-Luisa 0001315018 4 34 001-39202 20576278 1223 FOXGLOVE LANE WEST CHESTER PA 19380 Annovis Bio, Inc. 0001477845 2834 262540421 DE 1231 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 610-727-3913 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 QR Pharma, Inc. 20091202 4 1 a4.xml 4 X0306 4 2020-01-31 0 0001477845 Annovis Bio, Inc. ANVS 0001315018 Maccecchini Maria-Luisa C/O ANNOVIS BIO, INC. 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 1 1 1 0 President and CEO Common Stock 2020-01-31 4 P 0 1600 6.00 A 207942 D Common Stock 2020-01-31 4 C 0 7937 A 215879 D Common Stock 2020-01-31 4 C 0 762896 A 978775 D Series A-1 Preferred Stock 2020-01-31 4 C 0 11111 0 D Common Stock 7937 0 D Series A Preferred Stock 2020-01-31 4 C 0 1068054 0 D Common Stock 762896 0 D The reporting person acquired these shares in the initial public offering ("IPO") of Annovis Bio, Inc. ("Annovis"). Each share of Series A-1 Preferred Stock automatically converted into common stock of Annovis upon the closing of the IPO at a conversion ratio of one for 0.7143. Each share of Series A Preferred Stock automatically converted into common stock of Annovis upon the closing of the IPO at a conversion ratio of one for 0.7143. /s/ Maria Maccecchini 2020-02-04