0001104659-20-081235 4/A 2 20200701 20200706 20200706 Hoffman Michael B 0001290208 4/A 34 001-39202 201013822 (203) 413-2200 1 GREENWICH OFFICE PARK GREENWICH CT 06831 Annovis Bio, Inc. 0001477845 2834 262540421 DE 1231 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 610-727-3913 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 QR Pharma, Inc. 20091202 4/A 1 a4a.xml 4/A FORM 4 OMB APPROVAL [ ] Check this OMB Number: box if no longer UNITED STATES SECURITIES AND EXCHANGE COMMISSION 3235-0287 subject to Washington, D.C. 20549 Estimated Section 16. Form STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF average burden 4 or Form 5 SECURITIES hours per obligations may response... 0.5 continue. See Instruction 1(b). Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940 1. Name and Address of Reporting 2. Issuer Name and Ticker 5. Relationship of Person * or Trading Symbol Reporting Person(s) to Hoffman Michael B Annovis Bio, Inc. [ ANVS ] Issuer (Check all applicable) __X__ Director __X__ (Last) (First) (Middle) 3. Date of Earliest 10% Owner C/O ANNOVIS BIO, INC., 1055 Transaction (MM/DD/YYYY) _____ Officer (give title WESTLAKES DRIVE, SUITE 300 7/1/2020 below) _____ Other (specify below) (Street) 4. If Amendment, Date 6. Individual or BERWYN, PA 19312 Original Filed Joint/Group Filing (Check (City) (State) (Zip) (MM/DD/YYYY) Applicable Line) 2/5/2020 _X _ Form filed by One Reporting Person ___ Form filed by More than One Reporting Person Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned 1.Title of Security 2. 2A. 3. Trans. 4. Securities 5. Amount of 6. Ownership 7. Nature of (Instr. 3) Trans. Deemed Code Acquired (A) or Securities Form: Direct Indirect Date Execution (Instr. 8) Disposed of (D) Beneficially (D) or Beneficial Date, if (Instr. 3, 4 and Owned Following Indirect (I) Ownership any 5) Reported (Instr. 4) (Instr. 4) Transaction(s) (Instr. 3 and (A) 4) or Code V Amount (D) Price Common Stock 1385889 (1) D Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities) 1. Title of 2. 3. Trans. Date 3A. 4. Trans. 5. Number of 6. Date Exercisable 7. Title and Amount 8. Price 9. Number of 10. 11. Nature Derivate Conversion Deemed Code Derivative and Expiration Date of Securities of derivative Ownership of Security or Execution (Instr. 8) Securities Underlying Derivative Derivative Securities Form of Indirect (Instr. 3) Exercise Date, if Acquired (A) or Security Security Beneficially Derivative Beneficial Price of any Disposed of (D) (Instr. 3 and 4) (Instr. 5) Owned Security: Ownership Derivative (Instr. 3, 4 and Following Direct (D) (Instr. 4) Security 5) Reported or Transaction(s) Indirect Date Expiration Amount or (Instr. 4) (I) Exercisable Date Title Number of (Instr. 4) Code V (A) (D) Shares Stock Option $4.39 7/1/2020 A 30000 7/1/2020 7/1/2030 Common 30000 $0 30000 D (right to buy) Stock Explanation of Responses: (1) On February 5, 2020, the reporting person filed a Form 4 that inadvertently reported that he directly owned 1,400,175 shares of common stock instead of 1,385,889 shares of common stock directly owned by the reporting person. Remarks: Exhibit 24 - Power of Attorney Reporting Owners Reporting Owner Name / Address Relationships Director 10% Owner Officer Other Hoffman Michael B C/O ANNOVIS BIO, INC. X X 1055 WESTLAKES DRIVE, SUITE 300 BERWYN, PA 19312 Signatures /s/ Jeffrey McGroarty, Attorney-in-Fact for Michael Hoffman 7/6/2020 ** Signature of Reporting Person Date Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly. * If the form is filed by more than one reporting person, see Instruction 4(b)(v). ** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a). Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure. Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB control number. EX-24 2 ex-24.htm EX-24 Exhibit 24 POWER OF ATTORNEY Know all by these presents that the undersigned hereby constitutes and appoints each of Maria Maccecchini and Jeffrey McGroarty, and any of their substitutes, signing singly, as the undersignedís true and lawful attorney-in-fact to: 1. execute for and on behalf of the undersigned, in the undersignedís capacity as a director and officer of Annovis Bio, Inc. (the ďCompanyĒ), Forms 3, 4, and 5 in accordance with Section 16(a) of the Securities Exchange Act of 1934 and the rules thereunder; 2. do and perform any and all acts for and on behalf of the undersigned which may be necessary or desirable to complete and execute any such Form 3, 4, or 5, complete and execute any amendment or amendments thereto, and timely file such form with the U.S. Securities and Exchange Commission (the ďSECĒ) and any securities exchange or similar authority; and 3. take any other action of any type whatsoever in connection with the foregoing which, in the opinion of such attorney-in-fact, may be of benefit to, in the best interest of, or legally required by, the undersigned, it being understood that the documents executed by such attorney-in-fact on behalf of the undersigned pursuant to this Power of Attorney shall be in such form and shall contain such terms and conditions as such attorney-in-fact may approve in such attorney-in- factís discretion. The undersigned hereby grants to each such attorney-in-fact full power and authority to do and perform any and every act and thing whatsoever requisite, necessary, or proper to be done in the exercise of any of the rights and powers herein granted, as fully to all intents and purposes as the undersigned might or could do if personally present, with full power of substitution or revocation, hereby ratifying and confirming all that each such attorney-in-fact, or such attorney-in-factís substitute or substitutes, shall lawfully do or cause to be done by virtue of this power of attorney and the rights and powers herein granted. The undersigned also ratifies hereby any action previously taken by each attorney-in-fact that would have been authorized by this power of attorney if it has been in effect at the time such action was taken. The undersigned acknowledges that each attorney-in-fact, in serving in such capacity at the request of the undersigned, is not assuming, nor is the Company assuming, any of the undersignedís responsibilities to comply with Section 16 of the Securities Exchange Act of 1934, as amended. This Power of Attorney shall remain in full force and effect until the undersigned is no longer required to file Forms 3, 4, and 5 with respect to the undersignedís holdings of and transactions in securities issued by the Company, unless earlier revoked by the undersigned in a signed writing delivered to each of the foregoing attorneys-in-fact. IN WITNESS WHEREOF, the undersigned has caused this Power of Attorney to be executed as of this 6th day of July 2020. /s/ Michael Hoffman Michael Hoffman --------------------------------------------------------------------------------