0001104659-23-120305 4 1 20231120 20231121 20231121 McCarthy Reid 0001857733 4 34 001-39202 231426803 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 Annovis Bio, Inc. 0001477845 2834 262540421 DE 1231 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 610-727-3913 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 QR Pharma, Inc. 20091202 4 1 tm2331305d6_4seq1.xml OWNERSHIP DOCUMENT X0508 4 2023-11-20 0 0001477845 Annovis Bio, Inc. ANVS 0001857733 McCarthy Reid C/O ANNOVIS BIO, INC. 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 1 0 0 0 0 Common Stock 2023-11-20 4 A 0 824 6.07 A 8129 D /s/ Henrey Hagopian III, Attorney-in-Fact for Reid McCarthy 2023-11-21