0001104659-23-120749 4/A 1 20231120 20231122 20231122 Bruck Claudine 0001733680 4/A 34 001-39202 231433646 4995 BRADENTON AVE, SUITE 240 DUBLIN OH 43017-3552 Annovis Bio, Inc. 0001477845 2834 262540421 DE 1231 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 610-727-3913 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 QR Pharma, Inc. 20091202 4/A 1 tm2331305-7_4aseq1.xml OWNERSHIP DOCUMENT X0508 4/A 2023-11-20 2023-11-21 0 0001477845 Annovis Bio, Inc. ANVS 0001733680 Bruck Claudine C/O ANNOVIS BIO, INC. 1055 WESTLAKES DRIVE, SUITE 300 BERWYN PA 19312 1 0 0 0 0 Common Stock 2023-11-20 4 J 0 0 0 A 6567 D This amendment is being filed solely to reverse the previously reported purchase on the original form 4 filed on November 21, 2023 (the "Original Form 4"). Such purchase was rescinded by the registrant and the reporting person on November 22, 2023. /s/ Henrey Hagopian III, Attorney-in-Fact for Claudine Bruck 2023-11-22